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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d0048c6cf585374a47f555bace9a51d68c5754b4c1a806ecc7a2b404db49874' 
  AND token = 'a7xtrWaAefGdsxMmaAHClF0T2jBzxkq6Y8NafIpMW24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}