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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1416f86e75ecb9510bf9e9505186f4b001dd9509ed6df8b62c81d355c50da62a' 
  AND token = 'qUAhrRB/mKbXqQXG+0ZySJt8Xdw1ckKpghxZWGcxItU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}