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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e2c3e4a5035ae54198762d3da3f9f9d1b9176f9fafe74e0b62ce1e2b175c8e2' 
  AND token = 'P6QihEP15SfATLjAVJi/3oYY/c02QqNYZLpRtI9QQEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}