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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1a53feaf70ec2e2e25c57017e4e785a32dc280e0fbd2553e2b87637ed97f1bb' 
  AND token = 'RIwukT6WiGKFfPk5vy4haKEkMThc0L0zVyHs9JdzJGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}