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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a226dfa7545b440f675176e993f6785019988574287e2f995dfaa903529b699c' 
  AND token = '2ShfM2LMqDl8X55HhYgdS+rDJqmBaldws88i3RPOr1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}