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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a196fe721e687e800621ff6b0a2f1d0e06898635a83bb2f5043dc5354fb8893' 
  AND token = '+dnmsdDEOpuGtLfEN+oi9oAmMeTQQcXtgj1rbCa+U6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}