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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bec84885babcf0da76ec755bd7a6d3bb1015776b521809c583992379c4adef3' 
  AND token = 'd72RtT/e0OzOtHbIoOCa10oiA9zFQmEaNf4FIU35Ed4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}