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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4bd86788ae25055993da989887fbf8bf1a3245c8f0af50f7e031e8d52e57568' 
  AND token = 'sIbYW7jnnCbzHcbm3SjYJXEP0WVI7j0ZAoQ/eZb1W7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}