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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6e22c64447096dd8710329f97027dbca9ca4ff9af8d4cbdfe195e0e367f5ed5' 
  AND token = 'ttsYn0QN7Z7D4Gvr0WMLu8L5QD/zt6uypKk9/yxtlro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}