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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4edeb26d0645554e337fa750f48011255cfc69bf9f1e6e94562bc99e10da2052' 
  AND token = '87Ifqb910LznPioYV3owU4OVYSf1geLq5RL/6pQF8m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}