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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ebd7fd22e2ff20f6a1fe72865aa935c5605940a9e99134773aa0ae092d3cac6' 
  AND token = 'AzISUFkd2nAyIjTEUubDKS+sMVvQMYNc8PHyO06Ef/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}