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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0c345ec4c0f68879ff54b7d6b2eb1b75011f1ddb7432f0e726a80a62d7242c' 
  AND token = 'cFTnc0ij7nCle8JSbqD9krNTfPVUWZOQAwYEE/NpYh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}