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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b27db6be0965783e4f213307e7dd34cb3c45c9a15885d7a433e0a50cb89e95' 
  AND token = 'YzRUM8p2L8qc+ZPfHH6FSSdp2kFn19fC7TtzSaisyPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}