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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c03b53d4fcc05629f8ad3263aea3aeb260402d08b43c510ff979de078df9bf58' 
  AND token = 'T6K+64V/qtP/a0j4dHnh3nCKqHdAKsToK4iIeRUuY4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}