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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e3f6654a331d23afb72cf19eea56e3c568e9c10a5c6a1e57fe596bba767cf0e' 
  AND token = 'yNs7PMyR4YcqHsTq476hHAQ9h/TepDUV4ksdsEY/ALQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}