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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c93d0baade5b755cbd5f77c3b35eddf27d814797221fae6ddd37ed18c6e643d' 
  AND token = '6u1EHkhSK/dlKDG7HVEn6PkPpuQInNqYcTMP9BvZdGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}