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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c2ce8fed586146617b68f4467f9d89439933df5a691992d619f78656fce2721' 
  AND token = '6R3JNamqOhXRB+wrrEXbmjAEAMgZijmO7Wo4PEnF0nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}