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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1618e1a1fcae9a19afde5384948de547176c6782b36ea7d7c0afc8905cf91a31' 
  AND token = '5uQTFOXH1HB9+lMdLOtnYfgMlm4tx69/hOTK7Nq9O78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}