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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd287c00ba4dfd54cbe6868a116f7865029e723293bce932094cd826fa2d87c1e' 
  AND token = 'Jf1rrWirz4lrfpae4N/iA9AtGKBhLme/VVnW75PtdJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}