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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a01279094be700389e5657122a7ad3c75dd49715d68c08c98dd820617e4771' 
  AND token = '/ycS4vhQymlyCT+2+zfcAkM+UQdn497hluY3N0Jq228=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}