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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1890fec3fe1f1d224102a209cd12213c5463a5c75a1f97f306c7125526b7b5ff' 
  AND token = 'izS3f4o4qnRal0KHj05NvOnmUZPPrb/JA+VEcDlhJsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}