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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb3c1591fa37055d63dccb742e1e8b55cf73d498b4450b225b87710d91a7dcb0' 
  AND token = 'lIcg8/+iFowqPI+TZOl8w8sZu9bWZoKnWRoS37jRC0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}