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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c76644be15cecf84931a4d5fb50ede3244913ba2abfc76cd2957b76a218da75' 
  AND token = 'wgbO1ZmWwkDou4AiRCbzPGttGSZOsee97Senlx0NsyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}