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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4275d370f3ee8e5897bed3e5a933eed781b102c062687cc9e4fc8f18e1ef2c9a' 
  AND token = '3sQIlQpEiebC0H9ZCkexfYWPpCgmiSm18RRcl07/mGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}