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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b75ff7d9462d3d582eb41e62db79be38f54b13b512fa62b609fd1c29e3dbf63' 
  AND token = 'M5B9M64msUPA1cMAgmx4JyBp5mGdauBAnqgJlRULgBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}