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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f49048041769b2ba81377f118699467e91fd3e15db3d1e975a250c217541282' 
  AND token = 'trp9p1ExDlEFePZro+gGMPqv995g1FXD30OW6NcJ8KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}