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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12b2e4fe8c1b0e2bcefd1c71dc7a5df3cf39861954217a0d4dba73e9355017fb' 
  AND token = 'XgHOhV05MxvMrwkQGO2p9hN/pDTBfKZEJaMAkiyvryo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}