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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49ef1ea0509b96de75c080a61f89e5c0f2090e152e9cf7e4595c6ad464191b6' 
  AND token = 'h4bKmsSPqwljHB/aqhuV6Sr4X3HzS3YRkVNLiaF5kY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}