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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9dd89bd86bafe8e26914e4067001ff4a6e448ffe9c5662f7c253f8758c6e94' 
  AND token = '4zKsDfhSY+S1awJFovmXpY7JHpCsQ8xAtbvTJw3c6no=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}