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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ea93c398dad5b4761f1f2d16b7fc4f440a61f565dc82ffc94301f64f05f609' 
  AND token = 'MbAkzawqODUfFoglE1/9UDo9VC3tvtWjtXl++wxLt4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}