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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404c988d18bc1c58b24b2610129efa9ce3c599319444078f9a954911514f278c' 
  AND token = '3CUCGxS1EiFwJ+tGs6pUSRo999n8yr+7gVllTsWy58k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}