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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f33fb8c7d00cb672ec3e37adb5307730d6218cea4dbe817eb7f4e0683bb0d7e' 
  AND token = 'DO9VPMEDKdV1g04BeGrwCf+b/f2S0qfzQ74g06g93Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}