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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e584cec384bb27f2840b133649eca7829a6a0012a5814d83494864927900d8' 
  AND token = '+0yyxihlbzvoqsh71G95CLpFtWdOO739p7pQIzohrcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}