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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca1947f4e4db5f6fe9dca6416449d2133c545722506268e76f7f1b764c4d05c' 
  AND token = 'Ya3/iVUfkqaBR4sQddpf0UWYgZMD5rkWZ5nJTcym8T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}