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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb0fb802c446ed0a664520831b1a646329a5298e57425700f85a6d428bd7713d' 
  AND token = 'pbamn3Nf5CQkVzZAUeSy7FLB3RT+L5GbcOt5+0dHNiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}