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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca4e8e1156d2358b4b51212204af8087e559b40876239f61ac5b63326bc6d25' 
  AND token = 'cgIbqcvdhpA2q6i1eUi6yqjZ5ZYai5p1brlOlQYjzbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}