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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dda8d4c843f5c710d65e2cc6cce24a4dcceb396e9872aba8a48db00385f5a531' 
  AND token = 'ZvAEIsWKkYbux7YH4eAMmv0r3Ycv92gEvc0wYIdDT9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}