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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2ad12cc810ffbdf549bb0faf2d75e7a0445e84b01bdf152fa0a20e0a1697d47' 
  AND token = 'HQkXUOVoKrxKXKNrFoU1p9tmbQNfGGuOpeiAtX4XwQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}