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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6914f3063a67a0aacb4d49b9ecf64a8e9e8ca761c170814bf333dcdee2a1a88e' 
  AND token = '9ZCat9SCUE/CuTClQKAzIahNeN0jNy20NMc2rrPetYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}