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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f803aad7983e3460e111427731f471d8ad0298e47ef01382dfa250860b400c8' 
  AND token = 'zPfNdP+0S/oDmUTlBm1d3xWGqLSuuMXte7H4/+kvSmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}