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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f9eb551b73401dfa4cc8efbfdbbd760d9734670c766e5c0d7df2730f7ff220' 
  AND token = '17R1+OeKmiqGEbJ2etxbM5AM3hLtc0pwYhBsz4XreZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}