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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21493128ece555f49d9e61f0a77d60322cb6b62a2353e5cf55a5eb573f0435f1' 
  AND token = 'ovKBhlJcq2tifhVzVGNzGkL8fhyLkoSCdfHX3/2tEAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}