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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2354cbe7047b90687e200ad1ef685226f4826629def03b9919b9b13e8cde1c1' 
  AND token = 'ywvEzcmlGutrEeTdf8WwGhE6QpZLvssgvAhppl46nq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}