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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8ffdf0efd55bc17eff866f145d75789c9aa92c9d7c94ef2843c1eedabf6623' 
  AND token = 'OJUH67gpsut4OOyUxh88yoJYBaTd0UOF3pSROQUgA80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}