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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4638674217413d4fce70ddc8fea76cfd338a835089f968b2d62ba1a6ca1d22' 
  AND token = '6UGlRlnW9gpuBE3aErBLy5qhnIryT66kjJp87g3i33E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}