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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78eff31205012e2170c95587c62a4d82286b111401fbfbe5e6eb1a4fe406604f' 
  AND token = 'VYNzV2rgEO5qdldOtnjH+msE07pPweJh30+bJxjjXK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}