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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7578e33b7f96e0e414c771dcb175ff03526eea9e0ebc1d27ef61ee67e0f018' 
  AND token = 'j19rl9zaddkyu0Xl3yYoPrH3f0qvAWmjvoDv5C9tA7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}