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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbfc08446bf768beca9284374f3fb21166660fb1e2bbe1f20e4f373d12e31127' 
  AND token = 'h5I2nJrstjvq7Nw6FTwpWCv6hk7rXNmc00m03hkmybo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}