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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '303e01ac61ca756ea2e3f43272bbe1d7253e53bb1094de7d48867eacc6c4241a' 
  AND token = 'qSOCaDV0D5yEpBre+s3Bj5xUsFaDnWBqihQgBnrFT74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}