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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '273c72aecb1194e4b9f0a58253d1875005a03f7ae2a930929df1036a3b3f8982' 
  AND token = 'Slm63U6Xtus6C7wBMx77AbzvqkGtAOFGljLUFC5DMoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}